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Clinical application of dexmedetomidine and nalbuphine as an adjuvant to 0.5% ropivacaine to ultrasound-guided erector spinae plane block in patients undergoing thoracic surgery

Clinical application of dexmedetomidine and nalbuphine as an adjuvant to 0.5% ropivacaine to ultrasound-guided erector spinae plane block in patients undergoing thoracic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900024498
Enrollment
Unknown
Registered
2019-07-13
Start date
2019-07-01
Completion date
Unknown
Last updated
2019-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic surgery

Interventions

Group 2:0.5% ropivacaine 28ml + dexmedetomidine 1ug/kg
Group 3:0.5% ropivacaine 28ml+ ?nalbuphine 20mg

Sponsors

The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: ASA I-III, aged 18-75 years old, normal cognitive function, can cooperate with the completion of the experiment.

Exclusion criteria

Exclusion criteria: 1) coagulation dysfunction; 2) puncture point infections; 3) allergic to local anesthetics or opioids; 4) analgesic drug addicts; 5) refusal of ESP blockade; 6) chronic pain, mental or nervous system disease; 7) serious disease of heart head blood-vessel, liver and kidney function.

Design outcomes

Primary

MeasureTime frame
VAS scores in static and dynamic conditions;

Secondary

MeasureTime frame
Duration of the block;The first time of effective pressing of electronic analgesia pump;Effective pressing times of electronic analgesia pump;Medication in operation;Complications such as nauseas?vomiting and pneumonia;postoperative hospitalization time;The dosage of analgesics added at the ward;

Countries

China

Contacts

Public ContactLi Yuanhai

The First Affiliated Hospital of Anhui Medical University

liyuanhai-1@163.com+86 13505697561

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026