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Evaluate the use of intranasally administered dexmedetomidine combination with ketamine as a premedication in children

Evaluate the use of intranasally administered dexmedetomidine combination with ketamine as a premedication in children

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900024479
Enrollment
Unknown
Registered
2019-07-13
Start date
2016-05-01
Completion date
Unknown
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sedation effects

Interventions

D1: received intranasal dexmedetomidine with 1 µg/kg
D2:received intranasal dexmedetomidine with 2 µg/kg
D1+K:received dexmedetomidine with 1 µg/kg in one nostril, then intranasal ketamine with 1mg/kg in another nostril, respectively.
D2+K: received dexmedetomidine with 2 µg/kg in one nostril, then intranasal ketamine with 1mg/kg in another nostril, respectively.

Sponsors

Children's Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Choose during March 2016 to June palatal pharyngoplasty, tonsil extirpate, American society of anesthesiologists (ASA) grade I ~ II, 155 cases of children aged 2 ~ 6 years old.

Exclusion criteria

Exclusion criteria: Children with upper respiratory tract infection, difficult airway, nasal deformity, cardiopulmonary dysfunction, neurological diseases, vital organ dysfunction, and currently using psychotropic drugs.

Design outcomes

Primary

MeasureTime frame
Sedation effects;

Countries

China

Contacts

Public ContactXu Ying

Children's Hospital of Chongqing Medical University

xuyingxy3066@126.com+86 13983409393

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026