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Application of FENO detection in the evaluation of perioperative pulmonary inflammation in patients with general anesthesia combined with COPD

Application of FENO detection in the evaluation of perioperative pulmonary inflammation in patients with general anesthesia combined with COPD

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900024477
Enrollment
Unknown
Registered
2019-07-13
Start date
2019-07-30
Completion date
Unknown
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary emphysema

Interventions

Experimental group and control group:NO

Sponsors

Fuling Central Hospital of Chongqing
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. The patients volunteered to participate in the study and signed the informed consent; 2. The diagnosis of COPD in the observation group was clear, but not in the control group; 3. Those aged 40-70 years, with cardiac function grades I-II and ASA II-III, without long-term smoking history or quitting smoking for more than 5 years; (4) The operation time was less than 4 hours and the bleeding was less than 100 ml.

Exclusion criteria

Exclusion criteria: 1. Sinusitis, allergic diseases, sleep apnea syndrome; 2. Stroke history, psychosis, epilepsy, Parkinson's disease history, MMSE 11.1 mmol/L); (2) Patients with acute myocardial infarction within 1 month; (3) According to the New York Heart Association (NYHA) classification, cardiac function (> III); 5. unable to communicate accurately with words.

Design outcomes

Primary

MeasureTime frame
Exhaled nitric oxide;

Secondary

MeasureTime frame
pulmonary function;Serum inflammatory blood markers;

Countries

China

Contacts

Public ContactKeyu He

Fuling Central Hospital of Chongqing

569682851@qq.com+86 13896573523

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026