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Effects of nebulized hypertonic saline on patients with severe community-acquired pneumonia requiring invasive mechanical ventilation

Effects of nebulized hypertonic saline on patients with severe community-acquired pneumonia requiring invasive mechanical ventilation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900024473
Enrollment
Unknown
Registered
2019-07-12
Start date
2019-07-12
Completion date
Unknown
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with severe community-acquired pneumonia

Interventions

1:nebulized 3% hypertonic saline
2:nebulized normal saline

Sponsors

Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Eligible patients included patients aged more than 18 years and patients with severe community-acquired pneumonia requiring invasive mechanical ventilation.

Exclusion criteria

Exclusion criteria: We excluded patients with malignant tumors, severe autoimmune system diseases, tuberculosis, pulmonary infection after organ transplantation, a history of severe allergies, non-infectious pulmonary interstitial diseases (connective tissue disease, pneumoconiosis), pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
sputum volume;sputum density;blood gas analysis index;white blood cell counts;body temperature;adverse events;—

Countries

China

Contacts

Public ContactJiao Xie

School of Nursing, Jilin University

1761458270@qq.com+86 15904416251

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026