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The effect of high-pressure artificial pneumothorax on circulating tumor cells and survival in patients with esophageal cancer after endoscopic esophagectomy

The effect of high-pressure artificial pneumothorax on circulating tumor cells and survival in patients with esophageal cancer after endoscopic esophagectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900024460
Enrollment
Unknown
Registered
2019-07-12
Start date
2019-08-01
Completion date
Unknown
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal Disease

Interventions

experimental group:conduct artificial pneumothorax
control group:do not conduct artificial pneumothorax

Sponsors

Thoracic Surgery Department, West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) patients aged 18 to 80 years; (2) patients with thoracic esophageal cancer who have preoperative and postoperative pathological reports confirming it is a malignant tumor; (3) patients did not accepted neoadjuvant radiotherapy and chemotherapy before surgery; (4) patients without other malignant tumors; (5) sign informed consent form and willing to attend this study.

Exclusion criteria

Exclusion criteria: (1) patients receiving neoadjuvant radiotherapy and chemotherapy before operation; (2) patients with carcinoma of cardia and cervical esophagus; (3) patients with distant metastasis; (4) patients with poor heart, lung, liver and kidney functions and cannot tolerate the surgery; (5) patients who do not receive circulating tumor cell testing.

Design outcomes

Primary

MeasureTime frame
The number of circulating tumor cells before and after operation;

Secondary

MeasureTime frame
Recurrence and metastasis of tumors during 3-year follow-up;Operation duration;Postoperative complications, including anastomotic leakage, pneumonia, atelectasis, pulmonary edema, chylothorax, etc.;Overall survival;

Countries

China

Contacts

Public ContactFeng Lin

West China Hospital, Sichuan University

linfeng0220@aliyun.com+86 18980606877

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026