schizophrenia
Conditions
Interventions
RTMS group:Risperidone+rTMS
Combined group:Risperidone+rTMS+family intervention
Family intervention group:Risperidone+family intervention
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.diagnosis of first episode schizophrenia based on the Diagnostic and Statistical Manual of Mental Disorders fourth ve rsion (DSM-IV) criteria and confirmed using the Structured Clinical Interview for DSM-IV (SCID); 2. has never been on antipsychotic medication before; 3. the PANSS total score >70 points 4. aged between 18 and 60 years; 5. no allergy to baicalin; 6. the weight increased by more than 7% after risperidone treatment compared with the baseline; 7. informed consent of patients and their families.
Exclusion criteria
Exclusion criteria: 1. diagnoses of autoimmune diseases, heartdiseases, hepatobiliary and gastrointestinal diseases, blood diseases, diabetes neurological diseases, or psychiatric diseases other than first episode schizophrenia; 2. a history of allergy and hormone therapy, and have received immunotherapy in the past month; 3. a history of using any antibiotic or anti-inflammatory agent in the past month; 4. pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BDNF; | — |
Countries
China
Contacts
Public ContactXueiqn Song
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed