Posthepatitis B cirrhosis
Conditions
Interventions
group of blood stasis and collateral obstruction syndrome in posthepatitis B cirrhosis:none
group of non-blood stasis and collateral obstruction syndrome in posthepatitis B cirrhosis:none
healthy control group:none
Sponsors
Tianjin Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 72 Years
Inclusion criteria
Inclusion criteria: 1 The age ranged from 18 to 72 years. 2 According to the diagnostic criteria of post-hepatitis B cirrhosis, serum HBsAg and/or HBV-DNA were positive for more than 6 months, and Child-Pugh grade was A-B; 3 Voluntary participants and signers of informed consent.
Exclusion criteria
Exclusion criteria: 1 Patients with liver diseases caused by other viral infections besides hepatitis B virus (HBV); 2 Patients with severe autoimmune liver disease and drug-induced liver injury; 3 Inflammatory bowel disease, irritable bowel syndrome and malignant tumors, immune system diseases or the history of immunosuppressive agents; 4 In the past month, antibiotics, gastrointestinal motility drugs and intestinal microecological regulators were used. 5 Travellers who have been to endemic diarrhea areas in the past six months; 6 Psychiatric patients; 7 Pregnant or pregnant women and lactating women; 8 Allergic constitution and allergic patients; 9 Participate in other clinical trials within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sequencing analysis of 16S rDNA in feces;Full spectrum analysis of fecal bile acids; | — |
Countries
China
Contacts
Public ContactJianwei Jia
Tianjin Second People's Hospital
Outcome results
None listed