hypertension
Conditions
Interventions
Group of discontinued application of ACEI/ARB medication:discontinued application of ACEI/ARB medication preoperative
Group of continued application of ACEI/ARB medication:continued application of ACEI/ARB medication preoperative
Sponsors
Department of Anesthesiology, Central Theater Command General Hospital of the Chinese People's Liberation
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1 Adult patients with hypertension and 18 years or older, receiving ACEI or ARB therapy regularly for HTN in morning for >6 weeks and keeping biood pressure stable; 2 ASA physical status II to III; 3 Normal left ventricular systolic function(EF>=55%); 4 Patients with noncardiovascular surgery. 5 Patients with general anesthesia
Exclusion criteria
Exclusion criteria: 1 Patients with emergency surgery or neurosurgery; 2 Pregnant patients; 3 Patients with heart failure (NYHA>=2); 4 Patients with malignant arrhythmia,such as Atrial fibrillation, atrial flapping, frequent premature ventricular beats, ventricular tachycardia, grade III atrioventricular block, pathological sinus node syndrome; 5 Patients with myocardial infarction within 6 monthes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preoperative elevated blood pressure;Intraoperative refractory hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| Stroke rate within 7 days after surgery;Myocardial injury within 7 days after surgery;Renal function impairment within 7 days after surgery;Mortality rate within 7 days after surgery; | — |
Countries
China
Contacts
Public ContactLi Bixi
Department of Anesthesiology, Central Theater Command General Hospital of the Chinese People's Liberation
Outcome results
None listed