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Alleviation effect of probiotic supplement preparation on test anxiety via regulating intestinal microbiota

Alleviation effect of probiotic supplement preparation on test anxiety via regulating intestinal microbiota

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900024393
Enrollment
Unknown
Registered
2019-07-09
Start date
2019-07-10
Completion date
Unknown
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Test anxiety

Interventions

Anxiety group:Oral probiotics
Healthy group:Do not take probiotics orally

Sponsors

Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 24 Years

Inclusion criteria

Inclusion criteria: 1. Healthy group: selected according to the questionnaire results of the self-rating anxiety scale (total mean score of appendix 1 SCL90 1.5, or total score of attachment 2 HAMA (or attachment 3 Hamilton depression scale) >= 7 points) During the same period, 60 volunteers (male to female ratio 1:1) with anxiety symptoms were selected as the research objects in the campus. The performance was mainly characterized by depression, accompanied by at least 4 of the following items. (1) often inexplicable tension and anxiety; (2) like to complain, easily excited, some little things and temper, and hold on to; (3) lack of concentration, memory loss, fatigue, or energy loss; (4) with a series of physical symptoms.For example, sleep disorders, early awakening, insomnia, polysomnia, excessive sleep, etc.Or poor appetite, weight loss and so on; (5) always looking sad and unwilling to talk to others; (6) activities less, slow response. (6) have guilt or self-blame, self-evaluation is too low.

Exclusion criteria

Exclusion criteria: 1. Anxiety group: smoking and drinking; receiving anti-laxatives, dilators, probiotics, antispasmodic, antibiotics and other drugs within 30 days before enrollment; having severe heart, lung, kidney, liver dysfunction and metabolic diseases; receiving overdose and chemotherapy. 2. Healthy group: abnormal mental state, long-term insomnia, antibiotic treatment within 30 days before taking stool samples.

Design outcomes

Primary

MeasureTime frame
Fecal high-throughput sequencing;

Countries

China

Contacts

Public ContactTingtao Chen

Nanchang University

chentingtao1984@163.com+86 13979196862

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026