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Study on differential tsRNA expression of postherpetic neuralgia based on high-throughput sequencing

Study on differential tsRNA expression of postherpetic neuralgia based on high-throughput sequencing

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900024363
Enrollment
Unknown
Registered
2019-07-07
Start date
2019-07-08
Completion date
Unknown
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Herpes zoster

Interventions

The normal group, herpes zoster did not develop into PHN group, herpes zoster developed into PHN group, PHN group :no

Sponsors

The First Hospital of Jiaxing City / The First Affiliated Hospital of Jiaxing University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Before the rash, there are mild symptoms such as mild fatigue, low fever, loss of appetite, sensation of burning or neuralgia. It has obvious pain sensitivity, but it can also have no prodromal symptoms. 2. The diseased skin appears clustered with group blisters, and the peripheral nerves along one side are banded. 3. There may be obvious neuralgia, which may be dull pain, convulsion or migraine, often accompanied by burning sensation, mostly paroxysmal, or persistent with local lymphadenopathy. 4. Effective for targeted treatment with herpes zoster 5. American Society of Anesthesiologists (ASA) Grade I to II 6. Signing informed consent.

Exclusion criteria

Exclusion criteria: 1. Other body or local infections such as fever. 2. Sympathetic system diseases. 3. by drug or other physical therapy. 4. Mental illness. 5. Misdiagnosed (angina, intercostal neuralgia, gallstones, cholecystitis, appendicitis, etc.). 6. Other diseases (contact dermatitis, erysipelas, insect bite dermatitis, impetigo, bullous pemphigoid, etc.). 7. Follow-up treatment to exclude herpes zoster diagnoses.

Design outcomes

Primary

MeasureTime frame
tsRNA;

Countries

China

Contacts

Public ContactYao Ming

The First Hospital of Jiaxing City / The First Affiliated Hospital of Jiaxing University

kipobod@163.com+86 13758394990

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026