postoperative pain
Conditions
Interventions
Gold Standard:Clinical outcome
assessment 
of 
by 
Sponsors
the First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Sign the informed consent; 2. Laparoscopic nephrectomy for general anesthesia with endotracheal intubation; 3. Aged between 18-65 years; 4. American Society of Anesthesiologists (ASA) physical status classification of I or II; 5. body mass index (BMI) 18-32kg/m2; 6. The operation time less than 3 hours; 7. Agree to use postoperative analgesic pump.
Exclusion criteria
Exclusion criteria: 1. allergic to opioids or have other contraindications; 2. severe heart, lung and metabolic diseases; 3. recurrence of pain before surgery; 4. severe dehydration, electrolyte disturbance and shock; 5. liver and kidney functions obvious abnormal(relevant indicators are more than 2 times higher than normal); 6. a history of neuro-muscular system disease, mental illness, and a tendency to malignant hyperthermia; 7. Pregnancy, planned pregnancy or lactation; 8. history of chronic pain and long-term use of sedative and analgesic drugs (>3 months); 9. Drug or alcohol abusers; 10. Poor understanding or communication difficulty; 11. diagnosed with neuropathic pain; 12. Participated in additional drug clinical studies within the past 30 days; 13. severe hypertension; 14. failed to complete the data collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Consumption and demand of sufentanil; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative pain score at rest and exercise at each time point;Postoperative sedation score at each time point;overall satisfaction score;rescue analgesia ratio; | — |
Countries
China
Contacts
Public ContactWang Yanping
the First Affiliated Hospital of Zhengzhou University
Outcome results
None listed