Study for the effect of CYP1B1 genotype on angle dysgenesis and its clinical significance

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900024351

Enrollment

Unknown

Registered

2019-07-06

Start date

2019-08-01

Completion date

Unknown

Last updated

2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary congenital glaucoma

Interventions

Case series:None

Eligibility

Sex/Gender

All

Age

No minimum to 80 Years

Inclusion criteria

Inclusion criteria: Criteria for PCG diagnosis: having at least 2 or more following manifestations: (1) IOP>21mmHg with cornea diameter>12mm; (2) Haab's striae; (3) Cornea edema; (4) C/D enlarged. Criteria for JOAG diagnosis: (1) IOP>21mmHg; (2) Glaucomatous optical neuropathy; (3) Typical glaucomatous visual defect; (4) Open angle; (5) Aged 3 to 40 years.

Exclusion criteria

Exclusion criteria: (1) Secondary glaucoma; (2) Angle closure glaucoma; (3) With previous surgeries which severely affected the judgement of angle structure.

Design outcomes

Primary

Measure	Time frame
whole exome sequencing;Stage of angle dysgenesis;success rate of MAT surgery;	—

Countries

China

Contacts

Public ContactYan Shi

Beijing Tongren Eye Center

yansmile4433@163.com+86 18600446810

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026