Pancreatic cancer
Conditions
Interventions
Case series:SBRT WITH CONCURRENT CHEMOTHERAPY
Sponsors
Fujian Medical University Union Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Newly diagnosed patients, no radiotherapy or chemotherapy before the start of clinical trials; 2. Male or non-pregnant women aged 18-70 years old; 3. Histological or cytologically confirmed pancreatic cancer; 4. According to the Comprehensive Diagnosis and Treatment Guide for Pancreatic Cancer (2018) Edition)" junction can be resected or locally progressed to unresectable pancreatic cancer patients; 6. The maximum diameter of the lesion should not exceed 5 cm; 7. Hematological examination: White blood cell count >=3x10^9/L; Granulocytes >=1.5x10^9/L; Platelet count>=75x10^9/L; Hemoglobin>=100g/L; 8. Blood biochemical examination: AST / SGOT and ALT /SGPT 3 g/dL; Serum creatinine =70 points; 11. Patient's informed consent has been obtained.
Exclusion criteria
Exclusion criteria: 1. distant metastasis; 2. Patients with recurrent and distant metastasis; 3. History of other malignant tumors; 4. Have been treated with anti-cancer such as radiotherapy and/or chemotherapy; 5. Pregnancy or lactation women; 6. Spirit Abnormalities; 7. Severe heart, liver, and kidney dysfunction; 8. Gastric or duodenal obstruction 9. Peripheral sensory neuropathy grade > 1; 10. Patient non-compliance or the investigator believes that the patient is unable to complete the entire trial treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PFS; | — |
Secondary
| Measure | Time frame |
|---|---|
| TTF;ORR;OS;TEAE;Surgical resection rate and extent; | — |
Countries
China
Contacts
Public ContactBenhua Xu
Fujian Medical University Union Hospital
Outcome results
None listed