epithelial ovarian cancer
Conditions
Interventions
Sponsors
Oncology Department, Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18-75 years; (2) Epithelial ovarian cancer was diagnosed by pathology or cytology. (3) The stage of diagnosis is stage IV or after the previous radical treatment, recurrence and metastasis are re-staged to stage IV; (4) After the first-line and second-line treatmentthe tumor progresses again; (5) Behavioral status PS (ECOG) 0-2; (6) The estimated survival time is greater than 3 months; (7) Normal function of bone marrow, liver and kidney: Hb (hemoglobin) >= 80g / L; NEUT (neutrophil count) >= 1.5*10^9 / L; PLT (platelet) >= 90*10^9 / L; Alanine aminotransferase (ALT)= 30g / L; Creatinine (Scr) <= 1.5 * ULN; (8) Knowing to participate in the study, sign the informed consent, good compliance and can follow-up; (9) Women in childbearing age were negative for pregnancy test (blood/urine hCG) within 7 days. And ensured effective contraception during the trial and within 6 months after the end of the trial.
Exclusion criteria
Exclusion criteria: (1) Combined with hypertension and poor drug control, the blood pressure after standard antihypertensive treatment is higher than 140/90mmHg; (2) Combined bleeding risk; (3) Concomitant merger of other malignant tumors within five years; (4) Those who combine active tuberculosis and other serious infectious diseases; (5) Patients who have received radiotherapy; (6) Has received other anti-angiogenic drugs; (7) There are serious brain diseases or mental illnesses that affect the patient's ability to complain privately; (8) With the history of organ transplantation; (9) Participated in other clinical studies within 4 weeks; (10) Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression Free Survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall Survival;side effects; | — |
Countries
China
Contacts
Public ContactHaibo Zhang
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed