Osteoarthritis
Conditions
Interventions
Gold Standard:Clinical outcome: 1.Recurrent episodes of genual arthralgia for one month
2. X-ray shows asymmetric arthrostenosis, subchondral bone sclerosis and (or) cystic degeneration, and osteophytes of the joints
3. Synovial fluid is clear and viscous, and the WBC<2000ml
4. Morning stiffness<=30min
6. Bone friction sounds when&#
Index test:DECT and MRI
Sponsors
The First Affiliated Hospital of University of South China
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. aged >=40 years; 2. Those who voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. With history of knee trauma or surgery; 2. Mandatory spondylitis, rheumatoid arthritis, reactive arthritis, psoriatic arthritis or severe visceral lesions, severe metabolic disorders and bone tumors; 3. Those who had received immunosuppressant, adrenocortical hormone or systemic therapy before the trial; 4. Contraindications for MRI examination; 5. Poor image quality.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| bony and soft tissue structures of the knee; | — |
Countries
China
Contacts
Public ContactHeng Zhao
The First Affiliated Hospital of University of South China
Outcome results
None listed