Hypertension
Conditions
Interventions
intervention group:intervention guided by muscular oxygenation
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Aged under 65 years; 2) ASA I-III; 3) Essential hypertension patients scheduled for elective surgery; 4) Accept to participate in this study.
Exclusion criteria
Exclusion criteria: 1) Emergency surgery; 2) Simultaneous gastrointestinal surgery; 3) Anemia; 4) Preoperative chemotherapy or radiotherapy; 5) Neurological, cognitive or psychiatric disorders, including stroke, dementia, and schizophrenia with speech disorders, or any condition that makes meaningful post-operative visits impossible. 6) Cardiovascular diseases: low-output heart failure with preoperative left ventricular ejection fraction less than 30%, active coronary artery disease, severe cardiac valve disease with shortness of breath, symptomatic arrhythmia, pacemaker arrhythmia or AICD placement. 7) Pulmonary diseases: COPD needs home oxygen therapy, severe asthma needs steroid therapy or can not control steroids, and other lung diseases need home oxygen therapy. 8) Severe liver dysfunction (Child Pugh Class C and above). 9) Severe renal dysfunction (requiring renal replacement therapy). 10) Severe skeletal muscle diseases, such as muscle atrophy. 11) Skin disease and intolerance of noninvasive electrodes. 12) History of smoking.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic index;tissue oxygen saturation;Postoperative Simple Mental State Examination Scale (MMSE) Score;Postoperative complications such as hyperlacticemia, lower extremity venous thrombosis, pulmonary embolism, cerebral infarction, nausea and vomiting, and postoperative cognitive impairment occurred during hospitalization and 30 days after operation.;The patient's awake time, extubation time, and immediate OAA/S score after extubation.; | — |
Countries
China
Contacts
Public ContactAi Yanqiu
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed