chronic obstructive pulmonary disease
Conditions
Interventions
Index test:Ultrasound 
of 
muscle.
Sponsors
The First Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patients in stable phase of COPD or healthy volunteers who are 50-80 years old, 18.5-30 kg/m2 and no respiratory infections last 30 days will be enrolled in the study.
Exclusion criteria
Exclusion criteria: (1) chronic metabolic disorders; (2) neurological diseases or muscle diseases; (3) heart diseases; (4) took any drugs influencing skeletal muscles in the past 6 months; (5) a history of surgery in the past 3 months; (6) pneumothorax, pleural effusion, tuberculosis, bronchiectasis, pulmonary fibrosis or other serious respiratory diseases; (7) mentally disabled or subject insuitable to the study according to researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lung function;diaphragm shear wave velocity;intercostal muscle thickness;life quality score;nutritional indexs; SEN, SPE, ACC, PPV, NPV, AUC of ROC; | — |
Secondary
| Measure | Time frame |
|---|---|
| diaphragm thickness;diaphragm excursion;thickness of muscles of Lower limbs;CSA of muscles of Lower limbs; | — |
Countries
China
Contacts
Public ContactBin Chen
The First Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed