Discogenic low back pain
Conditions
Interventions
treatment group : lumbar intradiskal injection of Platelet-rich plasma
Control group:Intervertebral disc radiofrequency thermocoagulation
Sponsors
The Second Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The clinical diagnosis is discogenic low back pain, and Refractory low back pain persisting for >3 months. 2. Ineffective treatment of conservative treatment (oral medication, rehabilitation therapy, nerve block, etc.). 3. Maintained intervertebral disk height of at least 50%. 4. Disk protrusion less than 5 mm on magnetic resonance imaging or computed tomography scan. 5. Concordant pain on diskography. 6. Presence of a grade 3 or 4 annular fissure as determined by diskography. 7. Absent contraindications (eg, spinal stenosis).
Exclusion criteria
Exclusion criteria: 1. Coagulation disorders. 2. Currently used anticoagulation therapy. 3. Pregnant women. 4. Puncture site skin infection. 5. Contrast agent allergy. 6. There are mental illnesses (post-traumatic stress disorder, schizophrenia, etc.). 7. Intervertebral disc fusion, severe spinal stenosis, history of spinal surgery, vertebral spondylolisthesis, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SF-36 questionnaire;Oswestry Disability Index;VAS visual analogue pain scale; | — |
Countries
China
Contacts
Public ContactZhang Jianbo
The Second Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed