postherpetic neuralgia
Conditions
Interventions
Sponsors
Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) those who meet the diagnostic criteria for postherpetic neuralgia (2) aged 18 to 80 years; (3) body mass index (BMI) ranged from 18.0 to 25.0 (including 18.0 years old and 25.0 years old); (4) VAS score of 4-10 points (including 4 points and 10 points); (5) no satisfactory remission for at least 1 month after conservative pain treatment (e.g., antidepressants, anticonvulsants, tramadol, opioids, nerve block or damage, radiofrequency conditioning or damage); (6) voluntarily participate in the study and have signed the informed consent.
Exclusion criteria
Exclusion criteria: (1) people who are known to be allergic to dexmedetomidine and ketorolac amantinol; (2) inability to cooperate, such as lethargy, coma, confusion, delirium; (3) having a history of alcohol or drug abuse; (4) participants who have participated in other clinical trials within 12 weeks prior to or before the trial; (5) patients with pain syndrome (such as complex regional pain syndrome, spinal cord injury, diabetic multiple neuropathy, fibromyalgia); (6) patients with severe systemic diseases (including hypertension grade 2 or above, diabetes, myasthenia gravis, severe renal impairment, severe pulmonary dysfunction, shock, severe liver dysfunction, acute heart failure); (7) patients with infectious diseases (i.e. HIV, hepatitis b, syphilis); (8) severely infected; (9) patients with malignant tumors; (10) mental disorders (such as somatization disorders, schizophrenia, mania); (11) resting heart rate 100 times/min after ecg screening.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| T cell;Myeloid-derived suppressor cells;apolipoprotein E; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analogue score value;Depression score; | — |
Countries
China
Contacts
Public ContactQun Li
Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University
Outcome results
None listed