cardiac valve malfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. patients had mitral/tricuspid insufficiency; 2. patients had symptomatic and moderate-to-severe mitral stenosis; 3. patients had chronic and severe mitral regurgitation (cardiac function New York Heart Association or NYHA grade II-III) without severe left ventricular dysfunction (ejection fraction 55 mm; 4. patients had asymptomatic chronic severe mitral regurgitation, mild-to-moderate left ventricular dysfunction (ejection fraction of 0.30-0.60) and/or systolic late diameter >=40 mm; 5. unable to perform percutaneous balloon mitral valvuloplasty; 6. American Society of Anesthesia (ASA) grade IIs-III.
Exclusion criteria
Exclusion criteria: Additional contraindications for lung isolation and MICS, such as acute airway inflammation, laryngeal edema, tracheal compression, and coagulation dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vital sign after intubation;blood gas analysis before one-lung ventilation;blood gas analysis 30 minutes after one-lung ventilation;blood gas analysis 30 min after CPB;blood gas analysis 30 min before the end of the operation;mean airway pressure;airway peak pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| the times of intubation;the times of tube localization;the incidences of catheter displacement;the incidences of postoperative sore throat, and hoarseness;the time of cardiopulmonary bypass;vital sign before intubation;surgeons’ satisfaction with anesthesia; | — |
Countries
China
Contacts
Department of Anesthesiology, The Second Hospital of Jilin University