Post-stroke depression
Conditions
Interventions
depression one:transcranial magnetic stimulation
depression two:transcranial magnetic stimulation
control one:false stimulation
motor group:transcranial magnetic stimulation
control two:false stimulation
Sponsors
Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Previous history of subcortical stroke; (2) The onset time of stroke was 3 months to 1 year for non-acute stroke; (3) Aged 40 to 75 years; (4) HAMD (7-21 points), cesd-sc (> 20 points), FMA (50-95 points), Bs stage >=3, NIHSS < 12, conventional rehabilitation treatment; (5) Sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with acute stroke and cerebral trauma. (2) Intracranial infection, effusion or tumor occupation. (3) Intracranial metal and other foreign bodies (such as orthopedic materials, arterial clips, etc.). (4) The body has pacemaker, deep brain stimulator and other electronic equipment. (5) Previous seizures, including primary epilepsy and secondary epilepsy. (6) Severe complications after stroke, such as pneumonia and heart disease. (7) Previous history of depression and antidepressant use. (8) Cognitive dysfunction or aphasia (MMSE < 17). (9) Patients who cannot cooperate in neuropsychological testing; (10) Not following the prescribed treatment regimen and poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD-17;FMA;MMSE;HAM-A;Pittsburgh sleep scale;Brain MRI scan; | — |
Secondary
| Measure | Time frame |
|---|---|
| NIH Stroke Scale, NIHSS;Modified Rankin Scale;CESD-SC; | — |
Countries
China
Contacts
Public ContactSuiqiang Zhu
Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed