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New screening and diagnostic techniques and a subtype predictive scoring system based on real world data for the diagnosis of primary aldosteronism

New screening and diagnostic techniques and a subtype predictive scoring system based on real world data for the diagnosis of primary aldosteronism

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900024241
Enrollment
Unknown
Registered
2019-07-02
Start date
2019-07-08
Completion date
Unknown
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Aldosteronism

Interventions

Gold Standard:Recumbent saline infusion test, captopril challenge test, bilateral adrenal venous sampling, pathological results, postoperative clinical and biochemical results.
Index test:Urine&#32
aldosterone,&#32
plasma&#32
renin&#32
concentration,&#32
activity,&#32
angiotensin&#32
II.

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients over 18 years old, diagnosed with primary aldosteronism. 2. The patient is over 18 years old and diagnosed with essential hypertension.

Exclusion criteria

Exclusion criteria: 1. Renal insufficiency. 2. Severe cardiac insufficiency.

Design outcomes

Primary

MeasureTime frame
aldosterone;Renin activity;Angiotensin II;SEN, SPE, ACC, AUC of ROC;—

Countries

China

Contacts

Public ContactRen Yan

West China Hospital of Sichuan University

renyan@scu.edu.cn+86 18980601310

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026