Sepsis
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1 meet the diagnostic criteria of Sepsis 3.0; 2 aged 18 to 80 years; 3 sign the informed consent.
Exclusion criteria
Exclusion criteria: 1 the time of determination exceeds 48 hours; 2 pregnant or lactating women; 3 severe primary diseases that affect survival, including: uncontrolled malignant tumors that cannot be resected after metastasis, blood diseases and HIV; 4 continuous use of immunosuppressive agents or organ transplantation within the past 6 months; 5 continuous use of hormones 7 days before enrollment, which was converted into methylprednisolone dose >= 20mg/day; 6 participated in other clinical trials within 30 days; 7 the investigator judged that they could not complete the study or should not participate in the study (they were expected to die within 48 hours and refused active treatment).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone marrow cell morphology;Blood cell morphology;Bone marrow cell Colony-Forming test;Cytokine release test;Transcription factor detection;Transcriptome analysis;Phenotype of bone marrow cell;Phenotype of blood cell; | — |
Countries
China
Contacts
5 Haiyuncang Lane, Dongcheng District, Beijing