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Transfusion management of acute upper gastrointestinal hemorrhage in patients with ischemic heart disease

Transfusion management of acute upper gastrointestinal hemorrhage in patients with ischemic heart disease

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900024215
Enrollment
Unknown
Registered
2019-06-30
Start date
2019-06-30
Completion date
Unknown
Last updated
2019-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute upper gastrointestinal bleeding

Interventions

Group 2:Blood transfusions are performed when hemoglobin levels are below 100g/L, keeping hemoglobin concentrations between 100 and 120 g/L
Group 1:Blood transfusions are performed when hemoglobin levels are below 80g/L, keeping hemoglobin concentrations between 80 and 100 g/L

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1) Aged> 18 years old; 2) new acute upper gastrointestinal bleeding (hematemesis or black stool); 3) diagnosis of ischemic heart disease (including stable angina and acute coronary syndrome).

Exclusion criteria

Exclusion criteria: 1) refuse to receive blood transfusions; 2) refuse to participate in the study; 3) patients with malignant tumor or need long-term hemodialysis; 4) pregnant women; 5) O Rh negative blood; 6) the clinical score of Rockall was 0 or Hb =120 g/L; 7) gastrointestinal bleeding is related to trauma or surgery; 8) systemic diseases of the blood system; 9) currently included in other clinical studies.

Design outcomes

Primary

MeasureTime frame
All-cause mortality within 30 days;

Countries

China

Contacts

Public ContactYang Jinlin

Department of Gastroenterology, West China Hospital, Sichuan University

mouse-577@163.com+86 18980602058

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026