severe thermal injury
Conditions
Interventions
Gold Standard:Assessment of sepsis based on the 2007 American Burn Association (ABA) diagnostic criteria for burn sepsis.
immature 
granulocyte 
and 
Sponsors
Queen Elizabeth Hospital, Birmingham, UK
Eligibility
Sex/Gender
All
Age
1 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 1-15 years admitted with a >=20% TBSA; 2. Patients aged 16 and over admitted with a >=20% TBSA; 3. Volunteer to participate in the clinical trial and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Associated multiple injuries with Injury severity score > 25 ; 2. Decision not to treat made on admission due to the severity of the injury ; 3. Premorbid conditions:Active Malignancy,Patients receiving glucocorticoid treatment,Multiple limb amputations; 4. Any other condition not compatible with the study concerned by researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neutrophil function;the count of immature granulocyte;the level of plasma free DNA;SEN, SPE, ACC, AUC of ROC; | — |
Secondary
| Measure | Time frame |
|---|---|
| Multiple organ failure; | — |
Countries
China
Contacts
Public ContactJun Wu
The First Affiliated Hospital, Sun Yat-Sen University
Outcome results
None listed