Application of computed tomography angiography in the diagnosis of brain death in children

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900024211

Enrollment

Unknown

Registered

2019-06-30

Start date

2019-08-01

Completion date

Unknown

Last updated

2019-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain death

Interventions

Gold Standard:Diagnosis of brain death according to Criteria and practical guidance for determination of brain death in children.

Index test:Computed&#32

tomography&#32

angiography

Eligibility

Sex/Gender

All

Age

0.1 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Age range: 29 days to 18 years old; 2. Clear cause of coma; 3. Children were determined to be brain dead according to Criteria and practical guidance for determination of brain death in children; 4. The guardian of the child agrees to participate in this study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Use sedatives and hypnotics, antipsychotics, general anesthesia overdose, the effect of prolonged elimination or poisoning; 2. Low temperature (temperature of bladder or rectum <= 32 degree C); 3. hypotension, systolic blood pressure is lower than the normal low value of the same age; 4. Acute kidney injury; 5. Allergic history of iodine contrast agent.

Design outcomes

Primary

Measure	Time frame
Middle cerebral artery;Intracerebral vein;SEN, SPE, ACC, AUC of ROC;Kappa Consistency Analysis;	—

Countries

China

Contacts

Public ContactWang Quan

Beijing Children's Hospital, Capital Medical University

wq_bch@163.com+86 13370115030

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026