Endometrial preparation for frozen embryo transfer: a randomized controlled trial comparing modified natural regimen versus hormone therapy regimen

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900024192

Enrollment

Unknown

Registered

2019-06-29

Start date

2019-08-01

Completion date

Unknown

Last updated

2020-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

modified natural regimen:hCG 10000U for ovulation

hormone replacement therapy regimen:Progynova

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) Woman aged 21-40 years; 2) ovulatory cycles of 26-35 days; 3) frozen embryos; 4) first two FET cycles; 5) having >=1 good embryo or blastocyst per transfer; 6) written informed consent.

Exclusion criteria

Exclusion criteria: 1) Contraindication to estrogens or progesterone; 2) Uterine anomalies; 3) Recurrent implantation failure; 4) Endometrium <7 mm; 5) irregular menstrual period.

Design outcomes

Primary

Measure	Time frame
live birth rate of singletons;	—

Secondary

Measure	Time frame
overall rate of live birth;clinical pregnancy rate;miscarriage rate;multiple birth rate;cycle cancellation rate;maternal complications;neonatal morbidity;	—

Countries

China

Contacts

Public ContactLi Xue-Mei

Shenzhen Maternity and Child Healthcare Hospital

842326015@qq.com+86 13500052909

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026