Topic injection of tranexamic acid via a drain plus drain-clamping to reduce blood loss in adolescent idiopathic scoliosis surgery: a randomized controlled trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900024177

Enrollment

Unknown

Registered

2019-06-29

Start date

2019-07-01

Completion date

Unknown

Last updated

2019-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Scoliosis

Interventions

experimental group :Topic injection of tranexamic acid via a drain

control group:Saline

Eligibility

Sex/Gender

All

Age

10 Years to 19 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria were AIS patients underwent posterior fusion. We enrolled all of the patients who met the inclusion criteria and were willing to participate by giving written informed consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria included allergy to TXA, anemia (male hemoglobin 2.0 mg/dL), chronic liver disease, and pregnancy.

Design outcomes

Primary

Measure	Time frame
transfusion (U/pt);allogenic blood transfusion, n (%);hemovac drainage (mL);total blood loss;length of drainage (h);hemoglobin (g/dL);APTT;PT;D-Dimmer;	—

Secondary

Measure	Time frame
postoperative length of stay (d);	—

Countries

China

Contacts

Public ContactShen Jianxiong

Peking Union Medical College Hospital

shenjianxiong@medmail.com.cn+86 010 69252800

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 21, 2026