Skip to content

Early diagnosis of minimal hepatic encephalopathy based on multiscale dynamic functional connectivity

Early diagnosis of minimal hepatic encephalopathy based on multiscale dynamic functional connectivity

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900024168
Enrollment
Unknown
Registered
2019-06-28
Start date
2019-07-01
Completion date
Unknown
Last updated
2019-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

minimal hepatic encephalopathy

Interventions

Gold Standard:The expected normal reference value formulas of five PHES test items were established in the normal control group after education and age correction. The total score less than or equal t
connectivity&#32
based&#32
on&#32
fMRI.

Sponsors

Tianjin First Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Liver cirrhosis confirmed by clinical or imaging (CT, MRI or ultrasound); no obvious hepatic encephalopathy; normal vision; able to complete neuropsychological tests.

Exclusion criteria

Exclusion criteria: Contraindication or claustrophobia by MRI; other organic lesions in the brain (such as cerebral infarction, brain tumors, etc.) detected by conventional MRI; history of alcoholic cirrhosis or drug abuse, or taking drugs that affect cognition; excessive head movements during the examination affect data analysis.

Design outcomes

Primary

MeasureTime frame
dynamic functional connectivity;SEN, SPE, ACC, AUC of ROC;

Countries

China

Contacts

Public ContactYue Cheng

Tianjin First Central Hospital

chengyue200017076@163.com+86 13821559069

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026