Pre-Rheumatoid Arthritis
Conditions
Interventions
Sponsors
Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Meet the definition which we proposed of pre-RA; 2. The course of disease (first onset of joint involvement) between six weeks and six months; 3. Meet the diagnostic criteria of TCM syndrome of spleen deficiency and wind-damp blockade syndrome (Available in Table 2); 4. The patients aged 18–70 years; 5. The patients are willing to provide informed consent and adhere to this protocol.
Exclusion criteria
Exclusion criteria: 1) Patients were treated with DMARDs or hydroxychloroquine within 2 months when agreeing to participate in this study; 2) Patients were treated with glucocorticoids; 3) Patients who suffer from severe organ disease or mental illness; 4) Patients who are allergic or have contraindications to the drugs involved in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RA transition rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical disease activity index, CDAI;Simplified disease activity index, SDAI;Visual Analogue Scale/Score, VAS;patient's global assessment ofdisease activity, PGA;physician's global assessment of disease activity, MDGA;Patent scores;color Doppler ultrasound semi-quantitative score of joints; | — |
Countries
China
Contacts
Public ContactChengping Wen
Zhejiang Chinese Medical University
Outcome results
None listed