Urolithiasis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 to 60 years who had been diagnosed with upper urinary calculi,1.0-2.0 cm in size, by b-ultrasonography,KUB, IVP or non-enhanced computed tomography (CT). 2. All of them were completed by clinicians with more than 100 cases of experience and proficient in the operation of flexible ureteroscope lithotripsy. 3. Ureteroscopic lithotripsy was performed successfully without perforation of ureter, exfoliation of mucosa and injury of kidney and bladder. 4. Willing to participate in this study and actively cooperate with follow-up.
Exclusion criteria
Exclusion criteria: 1. Pregnancy, severe diabetes mellitus and renal insufficiency; 2. History of previous ipsilateral surgery or natural lithotripsy; 3. Patients with lower urinary tract obstruction; 4. Patients with incarcerated or infectious stones; 5. Preoperative reserved ureteral stent patients; 6. Taking alpha-1 receptor blockers and Chinese patent medicines which may affect the evaluation of the efficacy of lithotripsy within two weeks or allergic to experimental drugs; 7. Those who fail to use drugs according to the prescription can not judge the curative effect, or whose data are incomplete, which affects the judgement of effectiveness and safety; 8. Serious adverse events occur, and it is not appropriate to carry out the test again.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| stone excretion rate;stone free rate;stone composition; | — |
Secondary
| Measure | Time frame |
|---|---|
| hematuria;pain;urinary tract infection; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Zhengzhou University