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Association between driving pressure and postoperative pulmonary complications after lung cancer resection: a prospective randomized controlled study

Association between driving pressure and postoperative pulmonary complications after lung cancer resection: a prospective randomized controlled study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900024130
Enrollment
Unknown
Registered
2019-06-26
Start date
2019-06-25
Completion date
Unknown
Last updated
2019-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pulmonary complications after lung cancer resection

Interventions

Group D:driving pressure
Group P:PEEP 4

Sponsors

Sun Yat-Sen University Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. ASA physical status I ~ III; 2. Patients aged 19~75 years; 3. Patients undergoing lung cancer resection with single lung ventilation; 4. Patients with with cardiac function grade I ~ II assessed by electrocardiogram, echocardiography; 5. Food or semi-liquid intake is acceptable.

Exclusion criteria

Exclusion criteria: 1. Preoperative FEV1/FVC<50%; 2. Contraindication of PEEP: intracranial hypertension, bronchopleural fistula, hypoxic shock, right ventricular failure; 3. Involving drug allergy; 4. Patients with serious liver, kidney, hematopoietic system diseases; 5. Patients with serious complications such as pulmonary infection, atelectasis, emphysema, pulmonary heart disease and pleurisy; 6. Previous major chest surgery history or chemotherapy history.

Design outcomes

Primary

MeasureTime frame
postoperative pulmonary complications;

Countries

China

Contacts

Public ContactLonghui Cao

Sun Yat-Sen University Cancer Center

caolh@sysucc.org.cn+86 13826092036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026