Effect of intravenous injection of different doses of methylprednisolone on maternal fever rate and maternal and infant outcome in labor analgesia

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900024125

Enrollment

Unknown

Registered

2019-06-26

Start date

2019-07-01

Completion date

Unknown

Last updated

2019-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fever after labor analgesia

Interventions

Control:Intravenous preinjection of NS

treatment 1:intravenous injection of methylprednisolone 10mg

treatment 2:intravenous injection of methylprednisolone 20mg

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. The ASA I, II level, aged 20 to 45 years, single, full term (37 weeks to 41 + 6 weeks), head, choose natural childbirth puerpera. 2. The prenatal examination is suitable for vaginal delivery. 3. Approved by the hospital ethics committee. 4. Signing the informed consent.

Exclusion criteria

Exclusion criteria: 1. BMI >= 35 kg/m2; 2. Women in urgent labor; 3. Basal temperature >= 37.5 degree C; 4. Pathological pregnancy and obstetric complications; 5. Have or suspect intrauterine infection before analgesia; 6. Epidural analgesia failure. 7. Contraindication of spinal anesthesia. 8. History of alcohol or drug abuse.

Design outcomes

Primary

Measure	Time frame
Body temperature;	—

Countries

China

Contacts

Public ContactXu Shiyuan

Department of Anesthesiology, Zhujiang Hospital of Southern Medical University

xsy998@smu.edu.cn+86 13609727860

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026