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Effect of blood pressure control on prognosis in acute stage of large artery occlusive cerebral infarction

Effect of blood pressure control on prognosis in acute stage of large artery occlusive cerebral infarction

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900024121
Enrollment
Unknown
Registered
2019-06-26
Start date
2019-07-01
Completion date
Unknown
Last updated
2019-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardia-cerebrovascular Disease

Interventions

experimental group:reduce blood press
Control group:Blank control

Sponsors

The First Affiliated Hospital of Bengbu Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 89 Years

Inclusion criteria

Inclusion criteria: 1) age between 60 and 89 years old; 2) diagnosis of acute large artery occlusive cerebral infarction; 3) dyskinesia symptoms are caused by acute stroke rather than cerebral hemorrhage (excluded by brain CT scans); 4) admission with hypertension, systolic blood pressure between 140 and 180 mmHg.

Exclusion criteria

Exclusion criteria: 1) The modified Rankin scale (MRS) score before stroke was greater than 1; 2) the National Institutes of Health Stroke Scale (NIHSS) score was greater than 22; 3) there was a history of cerebral hemorrhage; 4) persistent hypertension (blood pressure > 220/> 120 mmHg) immediately before randomization; 5) end-stage coexisting systemic diseases, such as cancer, renal failure (creatinine > 200 micromol/L), cirrhosis, and severe cerebral hemorrhage. Dementia or psychosis; 6) Brain CT scan showed brain tumors or other significant non-ischemic brain damage; 7) thrombocytopenia (platelet count < 100 *10^9/L); 8) with severe heart failure, acute myocardial infarction or unstable angina pectoris, atrial fibrillation, aortic dissection, refractory hypertension and deep coma.

Design outcomes

Primary

MeasureTime frame
Cardia-cerebrovascular Disease mortality;Blood glucose;Blood lipid examination;Blood lipid examination;liver function;renal function;

Countries

China

Contacts

Public ContactHuadong Zhou

Department of Neurology, Daping Hospital

zhouhuad@163.com+86 13617670997

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026