Hyperhomocysteinemia associates with small vessel disease: expression of homocysteimia, UA, MMPs, CRP and PI

Hyperhomocysteinemia associates with small vessel disease: expression of homocysteimia, UA, MMPs, CRP and PI, and their relations

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900024120

Enrollment

Unknown

Registered

2019-06-26

Start date

2019-06-24

Completion date

Unknown

Last updated

2019-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperhomocysteinemia associates with small vessel disease

Interventions

WML:no intervention

LI:no intervention

Normal:no intervention

WML+LI:no intervention

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Standards for reporting vascularchanges on neuroimaging STRIVE Features seen on neuroimaging include recent small subcortical infarcts, lacunes, white matter hyperintensities, perivascular spaces, microbleeds, and brain atrophy. SVD can present as a stroke or cognitive decline, or can have few or no symptoms.

Exclusion criteria

Exclusion criteria: 1. aged below 35 years; 2. artery narrowness; 3. important organ diseases; 4. sever body diseases and so on; 5. using drugs affecting Hcy levels (P>0.05).

Design outcomes

Primary

Measure	Time frame
Hcy;MMP-9;CRP;UA;PI;	—

Countries

China

Contacts

Public ContactShina Shangguan

Affliated Hospital of Shandong Medical Colledge

maggie4426@163.com+86 15069950295

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026