Effects of sevoflurane combined with dexmedetomidine sedation on postoperative delirium and outcome in elderly patients undergoing hip replacement--A clinical multicenter randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900024115

Enrollment

Unknown

Registered

2019-06-26

Start date

2019-06-30

Completion date

Unknown

Last updated

2019-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

femoral neck fracture

Interventions

Experimental group:Dexmedetomidine and Sevoflurane

Control group:Sevoflurane

Eligibility

Sex/Gender

All

Age

65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. For patients planning to receive hip replacement surgery, ASA grade II to III; 2. Aged 65 to 80 years old; 3. Normal communication and learning ability; 4. Voluntary to be involved in and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Severe respiratory and circulatory diseases, such as severe coronary atherosclerosis, heart failure, myocardial infarction, respiratory failure and other basic diseases; 2. Neurological diseases, such as severe cerebral hemorrhage or cerebral infarction sequelae, hemiplegia, aphasia, etc.; 3, mental illness: such as schizophrenia, depression, etc.; 4. Excluding patients with infectious diseases and abnormal preoperative inflammatory indicators; 5. Complicated with obvious abnormal liver or kidney function.

Design outcomes

Primary

Measure	Time frame
postoperative delirium;Rammsay score;	—

Countries

China

Contacts

Public ContactYe Zhang

The second Affiliated Hospital of Anhui Medical University

zhangy1013@163.com+86 0551-63869485

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026