malignant biliary obstruction
Conditions
Interventions
Group 1:biliary stent loaded with radioactive 125I seeds (radioactive biliary stent, RBS)
Group 2:Conventional biliary stent loading
Sponsors
Qinhuangdao Municipal 1st Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 90 Years
Inclusion criteria
Inclusion criteria: Through clinical symptoms, signs and related auxiliary examinations, patients diagnosed as MBO are clearly. And obstruction site locates in the middle and low level of the bile duct (Bismuth-Corlette I and lower biliary obstruction). They have not undergone any surgical, interventional treatment and ERCP examination. There was no clear biliary infection and other infections before operation (no fever, white blood cells (WBC) counts are not exceeding 9x10^9 per unit, the percentage of neutrophils are not exceeding 70%). Antibiotics were not used in any form before surgery.
Exclusion criteria
Exclusion criteria: After surgery, there are typical fever symptoms within 1 week, and the body temperature rises by 1 degree C from the basic body temperature, and fever continues to occur for 3 days. The blood analysis within 1 week after surgery shows that the WBC counts exceed 10x10^9 per unit, and the percentage of neutrophils exceed 75%. Blood culture has bacteria. And the bilirubin doesnt decrease but increased.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The nosocomial infection rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pathogenic culture and identification; | — |
Countries
China
Contacts
Public ContactHongtao Niu
Qinhuangdao Municipal 1st Hospital
Outcome results
None listed