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Prospective study for chemoradiotherapy combined with unrelated donor umbilical cord blood transplantation for childhood neuroma

Prospective study for chemoradiotherapy combined with unrelated donor umbilical cord blood transplantation for childhood neuroma

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900024075
Enrollment
Unknown
Registered
2019-06-24
Start date
2019-07-01
Completion date
Unknown
Last updated
2019-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuroma

Interventions

Experimental group:unrelated cord blood transfusion
Control group:Conventional radiotherapy and chemotherapy

Sponsors

Third Affiliated Hospital of the Army Military Medical University (Daping Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Aged 6 to 18 years; 2. All cases were histologically confirmed by surgery or biopsy (gold standard for diagnosis of childhood tumors); 3. HIV virus is negative; 4. There is no obvious abnormality in liver and kidney function: ALT, AST <=2.5 times of normal upper limit, serum Cr and BUN <=1.25 times of normal upper limit; 5. Willing to follow the treatment plan, follow-up and laboratory testing as required; 6. Obtain informed consent signed by the patient or family member.

Exclusion criteria

Exclusion criteria: 1. With other history of congenital or immune disease; 2. Severe mental illness and cognitive impairment; 3. Severe allergies to biological agents; 4. There are obvious taboos on chemotherapeutic drugs; 5. Severe heart diseases, including myocardial infarction and cardiac insufficiency; 6. Any other situations in which researchers believe that patients should not participate in the this study.

Design outcomes

Primary

MeasureTime frame
Progression-free survival;Objective remission rate;

Secondary

MeasureTime frame
Quality of life score;Toxic side reaction;

Countries

China

Contacts

Public ContactMingying Geng

Third Affiliated Hospital of the Army Military Medical University (Daping Hospital)

380904661@qq.com+86 13708371600

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026