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Effects of Xuanbai Chengqi decoction on patients with pneumonia-derived?sepsis: a single-blind, randomised controlled trial

Effect of Xuan-Bai Cheng-Qi decoction enema on the level of inflammatory factors in alveolar lavage fluid of patients with sepsis pneumonia

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900024072
Enrollment
Unknown
Registered
2019-06-24
Start date
2019-08-01
Completion date
Unknown
Last updated
2019-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pneumonia-derived sepsis

Interventions

Sponsors

The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. The patients who meet the diagnosis of sepsis in traditional Chinese medicine are positive, the patients who meet the diagnostic criteria of sepsis in western medicine, and the patients who meet the diagnostic criteria of sepsis in western medicine; 2. Lung infected; 3. The initial APACHE II score more than 8; 4. Male and female aged 18 and 80 years; 5. Volunteer to participate in this study and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Sepsis shock; 2. Severe upper respiratory tract stenosis / obstruction, enlarged hemoptysis; 3. Active bleeding of digestive tract, fecal incontinence, intestinal perforation, mechanical intestinal obstruction; 4. Malignant tumor patients with advanced cachexia; 5. Patients with severe bleeding tendency and coagulation mechanism disorder; 6. Pregnant or lactating patients; 7. Persons with mental or legal disabilities (blind, deaf, dumb, mentally retarded, mentally disabled, physically disabled) and unable to cooperate; 8. Patients who are currently participating in or participated in other clinical trials within one month of this study; 9. Patients with other enema, fiberoptic bronchoscopy contraindications; 10. Syndrome differentiation of traditional Chinese medicine belongs to deficiency.

Design outcomes

Primary

MeasureTime frame
TNF-a, IL-6, HMGB-1 and IL-10;

Secondary

MeasureTime frame
TCM symptom score;

Countries

China

Contacts

Public ContactZhang Jun

The Second Affiliated Hospital of Guangzhou University of Chinese Medicine

13719429795@139.com+86 13719429795

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026