The sedative effect of different doses of dexmedetomidine on children undergoing cochlear implantation by nasal administration

Preoperative sedation of dexmedetomidine in children

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900024057

Enrollment

Unknown

Registered

2019-06-23

Start date

2019-06-24

Completion date

Unknown

Last updated

2019-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preoperative anxiety

Interventions

experimental group-1:Dextrometadiazine 0.5ug/kg

experimental group-2:Dextrometadiazine 1ug/kg

experimental group-3:Dextrometadiazine 1.5ug/kg

control group:5% Glucose and Sodium Chloride Solution

Eligibility

Sex/Gender

All

Age

0.5 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1. The ASA I - II; 2. Aged 6 months to 6 years; 3. A BMI of 28 or less; 4. Children scheduled for cochlear implantation.

Exclusion criteria

Exclusion criteria: 1. Respiratory diseases (allergic rhinitis, asthma, etc.); 2. Cardiac and hepatic insufficiency; 3. Heart block, abnormal heart rate; 4. Patients with neurological and psychiatric diseases.

Design outcomes

Primary

Measure	Time frame
Anxiety score;Preoperative sedation scores;Behavior scores;Cooperation degree during induction period;	—

Secondary

Measure	Time frame
RASS score;PEAD;	—

Countries

China

Contacts

Public ContactChen Yanping

Department of Anesthesiology, the Second Xiangya Hospital, Central South University

hershey_diane@yahoo.com+86 15973148398

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026