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Clinical study for predicting volume responsiveness in septic shock patients by using continuous non-invasive arterial pressure monitor during passive leg raising

Clinical study for predicting volume responsiveness in septic shock patients by using continuous non-invasive arterial pressure monitor during passive leg raising

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900024053
Enrollment
Unknown
Registered
2019-06-23
Start date
2019-06-25
Completion date
Unknown
Last updated
2019-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with septic shock

Interventions

Gold Standard:The variability of SV after volume expansion (VE) test is the gold standard for volume responsiveness.
pressure&#32
combined&#32
with&#32
(PLR)

Sponsors

Fujian Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Aged > 18 years; (2) According to the diagnosis of severe sepsis or septic shock, persistent hypotension, circulatory instability or tissue hypoperfusion are present; (3) agree to use CNAP for hemodynamic monitoring.

Exclusion criteria

Exclusion criteria: (1) Refusal to participate in the study; (2) Pregnant women; (3) Cardiopulmonary arrest; (4) Severe upper extremity arteriosclerosis; (5) absence of fingers or severe obesity, edema can not use finger cuffs; (6) uncontrolled patients with severe hemorrhagic diseases; (7) patients treated with intra-aortic balloon counterpulsation; (8) severe arrhythmia; (9) lower extremity braking, hand braking PLR can not be accomplished by amputation, venous thrombosis or phlebitis of lower extremity.

Design outcomes

Primary

MeasureTime frame
CO;SV;MAP;CVP;SVV;

Countries

China

Contacts

Public ContactXue Yimin

Fujian Provincial Hospital

xueyimin1987@163.com+86 18650771928

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026