Urethral and rectal chlamydia trachomatis infections
Conditions
Interventions
group B:Doxycycline regimen: 100 mg orally twice a day for 7 days
Sponsors
Dermatology Hospital of Southern Medical University
Eligibility
Sex/Gender
Male
Age
20 Years to 49 Years
Inclusion criteria
Inclusion criteria: 1. MSM; 2. Positive test for chlamydia trachomatis using PCR performed on specimens of urethral or/and rectal swabs; 3. Aged between 20 and 49 years; 4. Adequate comprehension skills to give informed consent; 5. Able to attend 3 weeks post-completion therapy follow-up visits and provide urethral and rectal swabs; 6. Commitment to have not sexual behaviors for the next 4 weeks after initiating treatment.
Exclusion criteria
Exclusion criteria: 1. Self-report of antibiotic use in the last 4 weeks; 2. Unwillingness to participate in the study or provide informed consent; 3. Unwillingness to attend follow-up visits; 4. Known allergy to macrolides and/or tetracyclines; 5. Self-reported cardiovascular conditions and concomitant use of QT-prolonging drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CT DNA in urethral or/and rectal swabs;Side effect report rate; | — |
Countries
China
Contacts
Public ContactLigang Yang
Dermatology Hospital of Southern Medical University
Outcome results
None listed