breast disease
Conditions
Interventions
non-antibiotics group:simple drainage without antibiotics
antibiotics group :drainage combined with antibiotics
Sponsors
Guangzhou Women and Children`s Medical Center
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria are: 1) Breastfeeding females, age ranging from 18 to 45 years; 2) Confirmed diagnosis of lactational breast abscess; 3) Measurable swelling by ultrasonography; 4) Obtainment of written informed consent before inclusion; 5) Awareness of trial details as well as agreement with study process, intervention and follow-up.
Exclusion criteria
Exclusion criteria: Exclusion criteria are: 1) Incapable of giving informed consent (eg: linguistic obstacle); 2) Concomitant vital organ dysfunction, hematological diseases, mental disorders; 3) History of breast carcinoma or history of breast surgeries; 4) Patients with surgical contradictions; 5) Suspicion of sepsis, or refractory infections; 6) Immunocompromised patients (eg: patients with history of chemotherapy, organ transplant and any immuno-deficient conditions); 7) Concomitant antibiotic usage for other indication; 8) Known allergy of study medications; 9) Repeated high fever with administration of antibiotics; 10) Patients with other infectious wounds.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| time to resolution of breast abscess;recurrence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| 3-day-improvement proportion;rate of continuing breastfeeding;length of hospital stay;procedure-related complications; | — |
Countries
China
Contacts
Public ContactGuanhua Li
Guangzhou Women and Children`s Medical Center
Outcome results
None listed