Effects of intra-operative end-tidal carbon dioxide levels on postoperative nausea and vomiting after thyroidectomy: a randomized controlled study

Effects of intra-operative end-tidal carbon dioxide levels on postoperative nausea and vomiting after thyroidectomy: a pilot randomized controlled study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900023997

Enrollment

Unknown

Registered

2019-06-21

Start date

2019-07-24

Completion date

Unknown

Last updated

2020-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid disease

Interventions

the mild hypercapnia group:PetCO2 45-50 mm Hg

the normocapnia group:PetCO2 30-35 mm Hg

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Aged 18-65 years; ASA I-II; Elective thyroid tumor resection;patients with low or moderate risk in PONV

Exclusion criteria

Exclusion criteria: known hypersensitivity to antiemetic drugs; documented significant systemic diseases; use of antiemetic drugs, opioids or glucocorticoids within 3 days before surgery; participation in another clinical trial; and pregnancy or breast-feeding.

Design outcomes

Secondary

Measure	Time frame
postoperative pain scores;rescue antiemetics;supplementary analgesics;duration of PACU stay;duration of hospitalization and duration of hospitalization after surgery;time to extubation;postoperative complications;	—

Primary

Measure	Time frame
the incidence of PONV;the recruitment rate and the retention rate;	—

Countries

China

Contacts

Public ContactKexuan Liu

Department of Anesthesiology, Nanfang Hospital, Southern Medical University

liukexuan705@163.com+86 13710684096

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026