The shedding of vascular endothelial glycocalyx layer in one-stage hybrid coronary revascularization procedure

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900023987

Enrollment

Unknown

Registered

2019-06-21

Start date

2019-12-02

Completion date

Unknown

Last updated

2021-12-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative vascular endothelial injury

Interventions

Hybrid group:None

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients undergoing one-stage hybrid coronary revascularization procedure; 2. Aged 35-75 years; 3. ASA I to III; 4. BMI 18.5-30; 5. Voluntary participation.

Exclusion criteria

Exclusion criteria: 1. Alcohol or substance abuse; 2. Abnormal renal function SCr >1.2mg/dl; 3. Acute myocardial infarction; 4. Uncontrolled diabetes.

Design outcomes

Primary

Measure	Time frame
Syndecan-1;Atrial natriuretic peptide, ANP;Heparan sulfate, HS;Serum albumin;IL-6;	—

Countries

China

Contacts

Public ContactWu Yan

Beijing Chaoyang Hospital Affiliated to Capital Medical University

yhanwu@sina.com+86 13651077828

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026