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The Effect and Safety of the Low-Carbohydrate, Ketogenic Diet on the Polycystic Ovary Syndrome: A Randomized Controlled Study

The Effect and Safety of the Low-Carbohydrate, Ketogenic Diet on the Polycystic Ovary Syndrome: A Randomized Controlled Study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900023979
Enrollment
Unknown
Registered
2019-06-20
Start date
2019-07-01
Completion date
Unknown
Last updated
2019-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome

Interventions

Traditional treatment group:Give balanced diet guidance and short-acting oral contraceptive treatment

Sponsors

Beijing Shijitan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-40 years; 2. According to the 2011 Chinese PCOS diagnostic criteria: menstrual thinning or amenorrhea or irregular uterine bleeding and meet one of the following two items: (1) high androgen clinical manifestations or hyperandrogenism; (2) ovarian polycystic Change by ultrasound. 3. The body mass index = 24Kg / m2, or body fat rate = 28%.

Exclusion criteria

Exclusion criteria: 1. Other diseases that cause hyperandrogenism or high androgen symptoms: (1) Cushing's syndrome; (2) Non-classical congenital adrenal hyperplasia (NCCAH); (3) Tumors that secrete androgen in the ovary or adrenal gland; (4) Drug-like Hyperandrogenemia; (5) Family history of idiopathic hairy positive; 2. Other diseases that cause ovulation disorders: (1) Functional hypothalamic amenorrhea; (2) Thyroid disease: high PRL: (3) Early onset ovarian insufficiency (POI); 3. Women who are breastfeeding, pregnant, perioperative, smoking or alcohol abuse; 4. Patients with liver and kidney dysfunction, pancreatic insufficiency, gallbladder disease, abdominal tumor or gastrointestinal disease, diabetes patients with hypoglycemic agents and insulin, hypertensive patients.

Design outcomes

Primary

MeasureTime frame
Body composition analysis;female hormones;Gynecological ultrasound;Menstrual cycle;Weight;Blood chemistry;Abdominal ultrasound;Blood routine;

Countries

China

Contacts

Public ContactBai Wenpei

Beijing Shijitan Hospital, Capital Medical University

bwp66@163.com+86 010-63926259

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026