Hepatocellular Carcinoma
Conditions
Interventions
Group 1:Liver transplantation after DEB-TACE
Sponsors
Shulan (Hangzhou) Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Meet the Hangzhou Standard: (1) No portal vein cancer thrombus; (2) The cumulative diameter of tumors is less than 8 cm or the cumulative diameter of tumor, or the cumulative diameter is 8 cm, the preoperative alpha-fetoprotein (AFP) 400 ng/ml, and the histological graded be high or moderately differentiated primary hepatocellular carcinoma; 2. Complete preoperative laboratory examinations, enhanced CT and/or MRI imaging of the liver were available. 3. Child Pugh liver function rating: A or better B (< 7 points); 4. ECOG PS score: 0.2; 5. Subjects volunteered to join the study, signed informed consent, good compliance, with follow-up.
Exclusion criteria
Exclusion criteria: 1. Patients with hepatobiliary cell carcinoma and metastatic hepatocellular carcinoma; 2. Those who have received surgery and RFA before; 3. BCLC stage 0 and A; 4. Child-Pugh liver function rating C or worse B (7 points); 5. Imaging findings such as CT or MRI suggest significant distant metastasis; 6. Complicated with severe infections such as liver abscess; 7. Patients with other malignant tumors that have not been effectively controlled; 8. patients with HIV infection; 9. Researchers judge other situations that may affect the conduct of clinical research and the outcome of research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| disease-free survival rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival;disease control rate;objective response rate; | — |
Countries
China
Contacts
Public ContactCao Guohong
Shulan (Hangzhou) Hospital
Outcome results
None listed