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Early Identification and Effective Management of Pediatric Sepsis

Integration of metabolic and inflammatory mediator profiles as a potential diagnostic approach for severe sepsis in PICU

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023958
Enrollment
Unknown
Registered
2019-06-19
Start date
2018-10-01
Completion date
Unknown
Last updated
2019-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

Gold Standard:Clinical outcome
Index test:metabolomisc&#32
and&#32
multiple&#32
inflammatory&#32
mediator&#32
profiling

Sponsors

Children's Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged from 29-day to 18-year old; 2. Sepsis is defined according to International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics, 2005.

Exclusion criteria

Exclusion criteria: 1. pre-existing sepsis; 2. primary immunodeficiency; immunosuppression state.

Design outcomes

Primary

MeasureTime frame
28-day in-hospital mortality;sever sepsis;SEN, SPE, ACC, AUC of ROC;—

Secondary

MeasureTime frame
MODS;length of ICU stay;secondary infection;—

Countries

China

Contacts

Public ContactLu Guoping

Children's Hospital of Fudan University

13788904150@163.com+86 13788904150

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026