Locally Advanced Gastric Cancer
Conditions
Interventions
Sponsors
the First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) 18 years old < age <75 years old; 2) gastric primary lesions were pathologically diagnosed by endoscopic biopsy as gastric adenocarcinoma (papillary adenocarcinoma pap, tubular adenocarcinoma tub, mucinous adenocarcinoma muc, imaged cell carcinoma sig, and poorly differentiated adenocarcinoma por); 3) preoperative clinical stages were t2-4a, n0-3 and M0(see preoperative evaluation plan for details). According to ajcc-7thtnm tumor stage); 4) it is expected that the results of RO surgery can be obtained by distal subtotal gastrectomy and D2 lymph node dissection (multiple primary cancers are also applicable); 5) preoperative ECOG physical state score 0/1; 6) preoperative ASA score i-iii; 7) informed consent of the patient.
Exclusion criteria
Exclusion criteria: 1) pregnant or lactating women; 2) severe mental illness; 3) history of upper abdominal surgery (except laparoscopic cholecystectomy); 4) history of gastric surgery (including ESD/EMR for gastric cancer); 5) preoperative imaging examination suggested regional fusion of enlarged lymph nodes (maximum diameter = 3cm) 6) history of other malignant diseases within 5 years; 7) gastric cancer patients who have been tested or recommended for neoadjuvant therapy; 8) history of unstable angina pectoris or myocardial infarction within 6 months; 9) a history of cerebral infarction or cerebral hemorrhage within 6 months; 10) a history of continuous systemic corticosteroid therapy within 1 month; 11) simultaneous surgical treatment for other diseases is required; 12) complications of gastric cancer (bleeding, perforation, obstruction) requiring emergency surgery; 13) lung function test FEVI< 50% of the estimated value.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3-year disease-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| 3-year overall survival;3-year locoregional recurrence rate;postoperative complication rate;Postoperative recovery time; postoperative 30-day mortality rate; | — |
Countries
China
Contacts
Public ContactTaiyuan Li
the First Affiliated Hospital of Nanchang University
Outcome results
None listed