Mechanism of Brain Network Plasticity Induced by Precision Sensory Cueing in Ischamic Stroke Patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900023926

Enrollment

Unknown

Registered

2019-06-18

Start date

2019-09-01

Completion date

Unknown

Last updated

2019-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Part 1 Chronic stroke:no

Part 1 Healthy:no

Part 2 Chronic stroke:no

Part 3 Experimental:Dynamic sensory cueing

Part 3 Placebo:Conventional training

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Part 1 Stroke participants: 1. first ischemic stroke and onset time more than 6 months; 2. Brunnstrom stage at 1-5; 3. aged 18 or above; 4. can follow the instructions; 5. no pain and edema affecting the movement of upper extremity. Health participants: matched persons according to the stroke patients in terms of age and illiteracy. Part 2 1. first ischemic stroke and onset time more than 6 months; 2. Brunnstrom stage at 1-5; 3. aged 18 or above; 4. can follow the instructions; 5. no pain and edema affecting the movement of upper extremity. Part 3: 1. first ischamic stroke on basal ganglia; 2. Brunnstrom stage at 1-5; 3. aged 18 or above; 4. can follow the instructions; 5. no pain and edema affecting the movement of upper extremity.

Exclusion criteria

Exclusion criteria: Part 1: 1. deny to participate the study; 2. botulinum toxin injection within 3 months; 3. cannot walk even using walk aid; 4. using medication or attending other research could affect the performance of upper extremity movement. Part 2: 1. deny to participate the study; 2. botulinum toxin injection within 3 months; 3. cannot walk even using walk aid; 4. using medication or attending other research could affect the performance of upper extremity movement. Part 3: 1. deny to participate the study; 2. botulinum toxin injection within 3 months; 3. cannot walk even using walk aid; 4. using medication or attending other research could affect the performance of upper extremity movement; 5. history of epilepsy.

Design outcomes

Primary

Measure	Time frame
Accelerometer data;Bold FMRI;DTI;TMS;Action Research Arm Test;	—

Secondary

Measure	Time frame
Fugl-Meyer Assessment;Box and Block Test;	—

Countries

China

Contacts

Public ContactWEI Xijun

Shenzhen Hospital, Southern Medical University

WeiXJ.OT@qq.com+86 13570386439

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026